Ciplukan contain "Fisalin compound" and "Withanolid" that was allegedly from the various reports containing anticancer activity. These plants also are cytotoxic in several cancer cells, could inhibit the growth of breast cancer cells MDA-MB 231, cell NCL-H23 lung adenocarcinoma, leukemia cells, and have anthihepatoma activity of human hepatoma cells Hep G2, Hep 3B, and PLC/PRF/5.
"From research conducted, confirm if ciplukan has the potential to be developed as an agent kemopreventif," said Ameilinda Monikawati on the campus of the University of Gadjah Mada (UGM) in Bulaksumur, Yogyakarta, on Wednesday (12/01/2010).
Benefits of these plants proved to inhibit breast cancer cells after the extract used. Extracts obtained from processing the "fruit ciplukan" which has eliminated the root.
Ameilinda said kemopreventif activity etanolik herb extract "ciplukan" be an alternative treatment of breast cancer patients. While breast cancer treatment with chemotherapy has been considered less effective. With chemotherapy often results in the resistance, as well as some side effects such as nausea, vomiting, toxicity to normal tissue, cardiac toxicity suppress the immune system.
"Because it takes an alternative cancer therapy safer, more affordable and effective," he said.
By "in vitro" of this research successfully suppress cancer cell growth by 20 percent. It's just not only in vitro, to support the research potential as an agent ciplukan kemopreventif on breast cancer test is also conducted in vivo. In vivo test is aimed to observe the effect of EHC on test animals strain Sprague Dawley female rats.
Technorati Tags: breast cancer, disease, cuplukan plant
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